Detailed case studies about microfluidic new product development will be given on the applications for disease diagnosis, prognosis and precision therapy, as well as the soft microfluidic wearable sensors for healthcare. Examples of emerging commercial microfluidic products (diagnostics cartridge, wearable systems, DNA amplification platforms) will be analysed during the sessions. The course also highlights on the applications of microfluidics and LOC, introduce the microfluidic components for life sciences, chemistry, point-of-care diagnostics, Organ on a Chip, etc. The MasterClass will discuss the fundamentals of microfluidics and Lab-on-a-Chip technology, including the fluid mechanics theory, microfabrication for microfluidics, characterization techniques, and the micro flow control. It has users who range in experience from school-age enthusiasts to retired integrated circuit designers. No prior microfluidics knowledge is required. MacSpice simulates and analyses electronic circuits that can range in complexity from a single resistor to an integrated circuit comprising tens-of-thousands of devices. The MasterClass is conducted by international leaders in microfluidics research, innovation and commercialization. SIMTech’s Microfluidics and LOC MasterClass aims at providing participants from industry, government laboratories, and academia, with state-of-the-art overview and analysis of current and emerging microfluidic and lab-on-a-chip technologies. Microfluidics offers high return on investment and helps in cost control by minimizing errors. The market is also driven by demand for high-throughput screening methodologies, low-volume sample analysis, demand for in Vitro Diagnostics (IVD), and development of advanced lab-on-a-chip technologies. The application of microfluidics has enabled conventional laboratory procedures to be shifted to Lab-on-a-Chip (LOC). Microfluidics-based devices need a fraction of the sample for data interpretation. Rise in demand for Point-of-Care (POC) devices is expected to significantly drive the market. The global microfluidics market is projected to reach USD 58.8 billion by 2026 from USD 20.7 billion in 2021, growing at a CAGR of 23.2%. This interdisciplinary field has a wide range of application areas including environmental sensing, medical diagnostics, drug discovery, drug delivery, microscale chemical production, combinatorial synthesis and assays, artificial organs, and micropropulsion, microscale energy systems. Microfluidics consists of components such as valves, pumps and mixers for manipulating and transporting the fluid at micrometer to nanometer scale. Biomicrofluidics (BMF) publishes research highlighting fundamental physiochemical mechanisms associated with microfluidic and nanofluidic phenomena as well as novel microfluidic and nanofluidic techniques for diagnostic, medical, biological, pharmaceutical, environmental and chemical applications. In a few words the shortest way to take part to the start-up ecosystem in the microfluidics domain. ![]() Register of Interest for SIMTech Course The Microfluidics degree (Master 2), associated to the Institut Pierre-Gilles de Gennes, is an interdisciplinary degree, oriented towards innovation and industrial applications.Multi-site Orders Allocation & Tracking.Life Cycle Assessment (LCA) and Life Cycle Costing (LCC).Sustainability & Emerging Applications Centre.Precision Engineering Centre of Innovation.Manufacturing Productivity Technology Centre.Sustainability & Lifecycle Engineering Division.FlexTech & MedTech Manufacturing Division.Lipid nanoparticles Microfluidic device RNA delivery mRNA vaccine.Ĭopyright © 2022 Elsevier B.V. In this review, we summarize microfluidic-based RNA-loaded LNP production and its applications in RNA-based therapy and genome editing. Microfluidics provides many advantages for RNA-loaded LNP production, including precise LNP size controllability, high reproducibility, high-throughput optimization of LNP formulation, and continuous LNP-production processes. Recently, microfluidic devices and technologies have attracted attention for the production of LNPs, particularly RNA-loaded LNPs. Download, install and launch MacSpice by following the instructions here: Installation Notes The first time you launch MacSpice it will create a working directory inside your Documents folder. Lipid nanoparticles (LNPs) are a breakthrough technology that stably delivers RNA to target organs, and RNA-loaded LNP-based nanomedicines have been studied for the development of vaccines and nanomedicines for RNA-, gene-, and cell-based therapies. ![]() The development of RNA-delivery technology, including mRNA vaccines, has been investigated worldwide for ~30 years. mRNA vaccines are important for preventing severe COVID-19 and returning to normal life. ![]() In 2021, mRNA vaccines against COVID-19 were approved by the Food and Drug Administration.
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